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WP1: Project and concept definition

The aim of this work package is

1) To develop a conceptual framework for achieving traceability of bio-molecules (nucleic acids and proteins) and bio-entities (cells) to the SI using higher order enumeration and purity assessments. Considerations will include:

  • Defining the concept of “measurand” for bio-molecules and bio-entities
  • Defining the concept of “purity” for bio-molecules and bio-entities
  • Defining metrological traceability chains appropriate to bio-measurement
  • Defining a strategy for assigning measurement uncertainty to quantities determined through enumeration and to purity values assigned to biomolecules and bio-entities taking stability of biomolecules in to consideration

2) To define the methodologies, experimental strategies, model systems, materials and measurement targets to be used in the experimental WPs (2-5)